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The best uterine tonic for a cow or buffalo after calving is one that matches the problem you are trying to prevent, has a clear label dose for your species, and does not leave residues in milk. For all-round transition support (uterus plus calcium and energy around calving), Cattle Remedies UTEROTONE 3 IN 1™ is our first pick. For routine uterine cleansing and involution, the classic UTEROTONE™ Liquid (since 1969) or its concentrated version UTEROTONE DS™ fits. A tonic supports normal recovery. It does not replace the vet when the placenta is retained, the cow has a fever, or the discharge smells foul.
After calving the uterus has to expel the placenta (usually within hours), drain the lochia (normal post-calving discharge) and shrink back to its normal size, a process called involution. When that goes wrong, through retained placenta, metritis or slow involution, the animal comes into heat late, conceives poorly and the calving interval stretches by months. In buffaloes, almost all of the variation in calving interval comes from the days between calving and conception (see our new guide to the buffalo calving interval). A clean, well-involuted uterus is where a short interval starts.
The practical lesson: use a uterine tonic to support normal recovery and as an adjuvant on your vet's advice, and invest in prevention through good transition feeding, minerals and hygienic calving.
| UTEROTONE 3 IN 1™ | UTEROTONE DS™ | UTEROTONE™ Liquid | |
|---|---|---|---|
| Best for | Transition support: uterus plus milk fever and ketosis risk, and milk production | Uterine cleansing and involution in a smaller-volume, concentrated dose | Classic uterine cleansing and involution after calving |
| What it contains | Herbs plus calcium 13,500 mg, phosphorus 6,750 mg and magnesium 200 mg per 100 ml, plus carbohydrate precursors | Ecbolic herbs with iron and copper | Ecbolic herbs with iron and copper |
| Cow / buffalo dose | 300 ml just before calving, 300 ml after 12 h, then 300 ml/day for 2–4 days (or 300 ml twice on the day of calving, then 300 ml/day for 2–4 days) | 50–65 ml twice daily for 4–5 days after calving | 100–125 ml twice daily for 4–5 days after calving |
| Retained placenta (label) | Indicated; follow your vet | Dose tripled and repeated every 3 hours until membranes are expelled, or as your vet directs | Dose tripled and repeated every 3 hours until membranes are expelled, or as your vet directs |
| Calcium per dose | About 40.5 g calcium and 20 g phosphorus per 300 ml dose (worked out from the label) | Not a calcium product | Not a calcium product |
| Packs | 300 ml, 900 ml | 250 ml, 500 ml | 225 ml, 450 ml, 900 ml, 5 L |
| Where to buy | Available on Amazon and at vet stores | Vet and medical stores | Vet and medical stores |
Doses are from the product labels. Always follow the pack or your veterinarian's advice. Ewe and doe doses are on each product page.
UTEROTONE™ गाय-भैंस के ब्याने के बाद बच्चेदानी (गर्भाशय) की सफ़ाई, जेर को समय पर गिराने और गर्भाशय को जल्दी सामान्य करने में मदद करने वाला हर्बल टॉनिक है। लेबल के अनुसार खुराक:
बुखार हो, बदबूदार स्राव हो, या ब्याने के 12 घंटे बाद भी जेर न गिरे, तो तुरंत पशु-चिकित्सक को बुलाएँ। जेर को हाथ से न खींचें।
Both are herbal uterine tonics with ecbolic herbs, iron and copper, and both are given twice daily for 4–5 days after calving. DS is the concentrated version: its label dose (50–65 ml) is about half the volume of UTEROTONE™ Liquid (100–125 ml).
The label states 13,500 mg calcium and 6,750 mg phosphorus per 100 ml. That works out to about 40.5 g calcium and 20 g phosphorus in each 300 ml dose.
Do not rely on it alone. Call your vet if the placenta is not out by about 12 hours. The tonic can be used alongside the vet's treatment. Never pull the placenta out by hand.
Yes. All three UTEROTONE™ products carry cow and buffalo doses, and the independent study above was done in buffaloes.
Keep UTEROTONE 3 IN 1™ for high-yielding or milk-fever-prone animals, and UTEROTONE™ Liquid or DS™ for routine use, so you can start within hours of calving.
Reviewed against the product labels and sources above on 22 October 2026. This guide is general information for dairy farmers, not a substitute for veterinary examination and treatment.
UTEROTONE is a polyherbal uterine tonic and ecbolic developed by Cattle Remedies, the animal-healthcare division of MAKAMS, founded in 1969. It is manufactured in-house under ISO, GMP and AYUSH standards and remains one of the most tried-and-trusted uterine tonics in Indian dairy farming — a genuine category pioneer rather than a recent entrant.
Synthetic hormonal ecbolics can act quickly but often carry withdrawal periods, milk residues and the risk of side effects when repeated. Herbal uterine tonics like UTEROTONE support the cow's natural recovery — aiding involution, cleansing and fertility — with no withdrawal period and a strong safety record, making them suitable for routine post-calving use across cows, buffaloes, goats and sheep.
UTEROTONE 3 IN 1 is available on Amazon: Buy UTEROTONE 3 IN 1 on Amazon.in. UTEROTONE Liquid and DS are stocked by veterinary and medical stores across North, East and West India — contact our team to find a stockist or for bulk supply. Explore the full range on our Cattle Remedies Amazon store.
A herbal, residue-free tonic that supports uterine cleansing and involution is ideal after calving. UTEROTONE by Cattle Remedies is widely used for this purpose; UTEROTONE 3 IN 1 is a popular choice as it also supplies calcium and energy precursors during the transition period.
Yes. UTEROTONE is herbal and residue-free, so it supports recovery without affecting milk quality and without the withdrawal periods associated with many synthetic drugs.
Dosage varies by product and animal — for example, the classic UTEROTONE Liquid is commonly given at 100–125 ml for cows and buffaloes, twice daily for a few days after calving. Always follow the pack instructions or your veterinarian's advice.
Yes — uterine tonics support timely expulsion of the placenta and regulation of lochial discharge. For retained placenta the dose is usually increased; follow veterinary guidance.
Yes. UTEROTONE is suitable for cows, buffaloes, goats and sheep, with the dose adjusted for the species and condition.
Need help choosing or want to become a stockist? Contact Cattle Remedies for product specifications, dealer locations and samples.
